Friday, March 12, 2010

another approach

Before I became a biomedical engineering major, I was at Loyola in Chicago as a biology major. While in biology obviously we learned just about everything atleast on a general level about cells and the human body. Learning about the Integumentary system was really something I found pretty interesting, especially how the layers of skin worked. Obviously most people know just from word of mouth that your skin is dead, atleast the outside layer (your epidermis). Have you ever stopped to wonder why? It's because of something called Keratin. Your dermis is impregnated by keratin before becoming your epidermis. The effect of cells becoming impregnated by keratin is they become water proofed, so water proofed that the cellular membrane becomes blocked off for any transport including simple osmosis (transport of water from high potential to low potential). This newly water proofed cell becomes starved for nutrients and dies. How effective is this? Well unless you start leaking and falling apart when you take a shower, odds are you're pretty water proofed. So while talking to my dad I had a thought. If Keratin does such a fantastic job at killing cells on a manageable level that doesnt effect our health, why hasnt a synthetic version of it been directed towards cancerous cells in localized areas to keep them from dividing and mulitplying, and killing them as simply as a skin cell dies. Granted I certainly do not know enough on the topic, however, I do think it's an approach that should be explored. Chemotherapy is extremely taxing to your entire body, it is effective in killing bad cells but it also kills many good cells. I am not saying keratin would not do the same thing, however your body would not be poisoned by keratin being injected into localized areas, it would essentially turn the bad stuff localized in a tumor into something more like the skin on your arm. Thoughts?

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